New Antidepressant Treatment Involves Transcranial Magnetic Stimulation

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Transcranial magnetic stimulation (TMS) is an experimental antidepression treatment that proved to be more effective than sham therapy in a large scale. A sham therapy, also called placebo therapy, is an inactive treatment or procedure that is intended to mimic as closely as possible a therapy in a clinical trial.

Though the experiment has not been approved by the FDA for antidepression treatment, an advisory panel for the agency found TMS to be safe. However, panel members also expressed doubts about the research showing the treatment to be effective.

TMS is a noninvasive procedure that requires no anesthesia and administered in an outpatient setting. This antidepression treatment sessions last from 30 to 45 minutes with patients reclining in a special chair while a specially placed coil device creates a magnetic field from outside of the body. This allows magnetic field to induce an electric current to regions of the brain thought to regulate mood.

Three hundred one patients with major depression who had failed to respond to antidepressant drugs participated in the experiment and half of them received TMS, which was given five times a week in 35-minute...

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