In 1999, glucosamine was the top-selling dietary supplement in the United States, with annual sales of US $288 million. It has become an immensely popular dietary supplement around the world.
It has proven itself again and again though its potential for repairing damaged joints and slowing the progression of arthritis.
Since glucosamine works so well for human arthritis, it is natural to ask: What about dog arthritis? Is it safe? Is it effective?
The answer: Yes, it appears to be both safe and effective.
The main safety concern comes from animal studies in which large amounts of glucosamine were given to rats and other animals intravenously, for short periods of time. Under these extreme and usual conditions, glucosamine tended to decrease insulin levels and/or induce insulin resistance. When researchers tested humans with large amounts of intravenous glucosamine, the same thing happened. Hence a concern arose that glucosamine could cause diabetes or make diabetes worse.
Normal therapeutic doses of glucosamine given orally have never been shown to have an adverse effect on insulin levels, insulin resistance or blood sugar levels. Even in...
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