In persons who are fairly normal these changes may be brought about very quickly by regulation of the diet and a voluntary effort to move the bowels after each meal; but in persons who have been chronically constipated for years, other measures are necessary. Means must be employed to combat chronic constipation systematically and continuously. It is not proper, how-ever, to resort to the habitual use of laxative drugs, such as castor oil, cascara sagrada, senna, etc. Salines and even laxative mineral waters must be avoided. All of these things do harm. They invariably aggravate the spastic condition of the descending colon almost always present.
Laxative drugs also produce an exaggeration of the anti-peristaltic movements, which begin in the transverse colon and travel backward toward the cecum. These movements are natural during digestion but do not interfere with the periodical movement of the intestinal contents. Colitis, rectal constipation and especially the use of laxative drugs greatly exaggerate this anti-peristaltic action and so increase the tendency to stasis in the cecum and the ascending part of the colon. It appears to be more than probable that this...
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