Human Growth Hormone Playing An Anabolic Role In The

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Human Growth Hormone Playing An Anabolic Role In The Body

HGH or human growth hormone is a protein hormone of 190 amino acids, which is synthesized and secreted by the Somatotroph cells (hence called Somatotropin) in the anterior pituitary. The genes for human growth hormone are localized in the q22-24 region of chromosome 17. The structure of HGH includes four helices necessary for functional interaction with the GH receptor. Structurally, HGH is homologous to prolactin and chorionic somatomammotropin and it appears as if the three share some evolutionarily connection. The triad is known to promote growth and aid the lactogenic activity.

Human Growth Hormone Secretion

Synthesis and secretion of HGH is controlled by many factors such as exercise, nutrition, sleep, stress and sometimes even by growth hormone itself. The control, however, are wielded by two hypo-thalamic hormones (Growth hormone-releasing hormone or GHRH and Somatostatin or SS) and one hormone present in the stomach (Ghrelin).

Functions of HGH

Human growth hormone contributes in the building up of the human body. HGH has two different types of effects on the human tissues...

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