Jhdma2a Gene: Hope Sparks for Curing Infertility

| Total Words: 537

A new discovery which plays a significant role in the development of sperm may be able to give light on the problem of male infertility. Scientists from Howard Hughes Medical Institute believe they have discovered that a defect in the Jhdma2a gene could cause some cases of infertility in men.
The Howard Hughes team noted that mice lacking the Jhdma2a gene were infertile and only produce tiny numbers of abnormal sperm. One of Britain’s leading male fertility experts expressed high hopes that the discovery could lead to some answers as to why there are some men who are incapable of fathering a child. Much of the reasons behind male sub-fertility remains vague to be fully understood.

Abnormally-shaped sperm or very low sperm count are two of the reasons why some men are not able to father a child. Many research studies are looking at genetic defects to be responsible for these conditions. The team of experts from Howard Hughes believed that the Jhdma2a gene is crucial for spermiogenesis which allows the DNA needed to create an embryo to be compacted into a tight ball inside the head of the sperm so that it can break through the outer surface of the egg. ...

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