A US study of 13,000 patients showed Tamoxifen reduced the rate of expected cancers from one in 130 to one in 236 – a cut of about 45%. The American researchers ended their trial early when they said the drug’s benefits became overwhelmingly obvious.
Other studies found that tamoxifen AND chemotherapy improved survival improved survival rates by about 4050% compared to taking one treatment or the other.
Should women taking tamoxifen avoid pregnancy?
Yes. Tamoxifen may make premenopausal women more fertile, but doctors advise women on tamoxifen to avoid pregnancy because animal studies have suggested that the use of tamoxifen in pregnancy can cause fetal harm. Women who have questions about fertility, birth control, or pregnancy should discuss their concerns with their doctor.
Does tamoxifen cause a woman to begin menopause?
Tamoxifen does not cause a woman to begin menopause, although it can cause some symptoms that are similar to those that may occur during menopause. In most premenopausal women taking tamoxifen, the ovaries continue to act normally and produce estrogen in the same or slightly increased amounts.
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